Investigations
What is an Investigation?
Erythropoietin (EPO) is a cytokine that serves, independent of hematopoiesis, signalling functions within the brain, where EPO and its receptor are upregulated upon injury. The underlying mechanisms, however, have remained obscure. We aim to understand the roles of EPO/EPOR signalling as checkpoints of brain homeostasis and thereby specifically predict effects of recombinant EPO as a neuroprotective drug. To this end, we will explore the induction/expression of EPO and EPOR at the single cell ...
Submitter: Camilla Giudici
Studies: Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s ..., Oligodendrocytes produce amyloid-β and contribute to plaque formation al...
Assays: Expression profiling: Bulk RNA-seq (mouse), Expression profiling: SuperSeries (mouse), Expression profiling: scRNA-seq (mouse), Expression profiling: snRNA-seq (human), Expression profiling: snRNA-seq (human), Expression profiling: snRNA-seq (mouse), Expression profiling: snRNA-seq (mouse)
