P20: Genome-wide in vitro reconstitution of cohesin-mediated loop extrusion to understand the interplay of chromatin architecture and gene expression
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https://gepris.dfg.de/project/559765651
started in 2025
Genomweite In-vitro-Rekonstitution von Cohesin vermittelter Loop-Extrusion zum Verständnis des Zusammenspiels von Chromatinarchitektur und Genexpression
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Created: 4th Sep 2026 at 08:50
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Projects: Default Project - for test purposes, CRC1002: Modulatory Units in Heart Failure, Cardiomyocyte tissues, TRR 274: Checkpoints of Central Nervous System Recovery, SFB 1190: Compartmental Gates and Contact Sites in Cells, MBExC: Multiscale Bioimaging, CRC 1565: Molecular mechanisms and interplay of gene expression processes, CRC 1690: Disease Mechanisms and Functional Restoration of Sensory and Motor Systems, SFB1690 Optogenetics Data - Demo project
Institutions: Default Institution, Universitätsmedizin Göttingen, University of Göttingen
https://orcid.org/0000-0002-9895-2469
https://gepris.dfg.de/gepris/projekt/469281184
While gene expression was traditionally viewed as a linear pathway of consecutive steps, we now know that genome organization and transcription, RNA processing and modification, RNA-protein complex assembly, translation and quality control are highly interconnected processes. Many cross-regulation events occur even between non-consecutive steps of gene expression, and even between processes taking place in different cellular compartments.
This paradigm ...
Programme: This Project is not associated with a Programme
Public web page: https://sfb1565.uni-goettingen.de/
