Investigations
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https://gepris.dfg.de/project/559765651
started in 2025
Genomweite In-vitro-Rekonstitution von Cohesin vermittelter Loop-Extrusion zum Verständnis des Zusammenspiels von Chromatinarchitektur und Genexpression
https://gepris.dfg.de/project/547467403
started in 2024
Das Zusammenspiel von mitochondrialen Ribosomen und der Qualitätskontrollmaschine
https://gepris.dfg.de/project/515956296
started in 2023
Verschaltungen der mitochondrialen Translationsmaschinerie
https://gepris.dfg.de/project/515955667
started in 2023
Mechanismen und Koordination zwischen Transkription und Ribosomenbiogenese in Mitochondrien
https://gepris.dfg.de/project/515952419
started in 2023
Der Einfluss gestörter Ribosomensynthese auf Transkription und Prä-mRNA-Spleißen in Wechselwirkung mit den Onkogenen MDM2 und MDM4
https://gepris.dfg.de/project/515951231
started 2023
Die Regulation nucleoplasmatischer Schritte in Genexpressionsprozessen durch die multifunktionelle RNA-Helikase DHX15 und ihre Kofaktoren
Erythropoietin (EPO) is a cytokine that serves, independent of hematopoiesis, signalling functions within the brain, where EPO and its receptor are upregulated upon injury. The underlying mechanisms, however, have remained obscure. We aim to understand the roles of EPO/EPOR signalling as checkpoints of brain homeostasis and thereby specifically predict effects of recombinant EPO as a neuroprotective drug. To this end, we will explore the induction/expression of EPO and EPOR at the single cell ...
Submitter: Camilla Giudici
Studies: Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s ..., Oligodendrocytes produce amyloid-β and contribute to plaque formation al...
Assays: Expression profiling: Bulk RNA-seq (mouse), Expression profiling: SuperSeries (mouse), Expression profiling: scRNA-seq (mouse), Expression profiling: snRNA-seq (human), Expression profiling: snRNA-seq (human), Expression profiling: snRNA-seq (mouse), Expression profiling: snRNA-seq (mouse)